Oxidative status of honey bees infected with Nosema ceranae microsporidium and supplemented with Agaricus bisporus mushroom extract

Nosema ceranae, a microsporidium species, is among the most common causes of bee diseases. The positive effect Agaricus bisporus mushroom extract on survival and immunity Nosema-infected bees has been reported recently. could be achieved by stimulating expression immune-related genes, but also suppressing nosemosis. aim this work was to determine A. oxidative status infected with N. ceranae. In cage experiment newly hatched bees, aqueous champignon (A. bisporus, strain A15) investigated. Six groups were formed: three received through food at different times (days 1, 3, 6 after hatching), one group not (treatment control), only (positive control) neither nor (negative control). effects examined samples taken days 7 15 study. activities antioxidant enzymes catalase (CAT), superoxide dismutase (SOD) glutathione S-transferase (GST) concentrations malondialdehyde (MDA) determined. comparison control, enzyme MDA significantly lower in fed supplement. negative level stress than control. other groups, values mostly did differ significantly. ceranae better if they extract.